The epithelioid BAP1-negative and p16-positive phenotype predicts prolonged survival in pleural mesothelioma.
Angela ChouChristopher W ToonAdele ClarksonAmy SheenLoretta SiosonAnthony J GillPublished in: Histopathology (2017)
In conclusion, p16 IHC is an independent prognostic biomarker in pleural mesothelioma. When used in combination with BAP1 IHC and morphological subtyping, patients with exceptionally prolonged survival can potentially be identified.
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