CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers.
Nichola JohnsonSarah MaguireAnna MorraPooja Middha KapoorKatarzyna TomczykMichael E JonesMinouk J SchoemakerClare GilhamManjeet K BollaQin WangJoe G DennisThomas U AhearnIrene L AndrulisHoda Anton-CulverNatalia N AntonenkovaVolker ArndtKristan J AronsonAnnelie AugustinssonCaroline BaynesLaura E Beane FreemanMatthias W BeckmannJavier BenitezMarina BermishevaCarl BlomqvistBram BoeckxNatalia V BogdanovaStig E BojesenHiltrud BrauchHermann BrennerBarbara BurwinkelDaniele CampaFrederico CanzianJose E CastelaoStephen J ChanockGeorgia Chenevix-TrenchChristine L Clarkenull nullDon M ConroyFergus J CouchAngela CoxSimon S CrossKamila CzeneThilo DörkA Heather EliassenChristoph EngelD Gareth EvansPeter Andreas FaschingJonine FigueroaGiuseppe FlorisHenrik FlygerManuela Gago-DominguezSusan M GapsturMontserrat García-ClosasMia M GaudetGraham G GilesMark S GoldbergAnna González-Neiranull nullPascal GuénelEric HahnenChristopher A HaimanNiclas HåkanssonPer HallUte HamannPatricia A HarringtonSteven N HartMaartje J HooningJohn L HopperAnthony HowellDavid J Hunternull nullnull nullAgnes JagerAnna JakubowskaEsther M JohnRudolf KaaksRenske KeemanElza KhusnutdinovaCari M KitaharaVeli-Matti KosmaStella KoutrosPeter KraftVessela N KristensenAllison W KurianDiether LambrechtsLoic Le MarchandMartha LinetJan LubińskiArto MannermaaSiranoush ManoukianSara MargolinJohn W M MartensDimitrios MavroudisRebecca MayesAlfons MeindlRoger L MilneSusan L NeuhausenHeli NevanlinnaWilliam G NewmanSune F NielsenBørge G NordestgaardNadia ObiAndrew F OlshanJanet E OlsonHåkan OlssonEster OrbanTjoung-Won Park-SimonPaolo PeterlongoDijana Plaseska-KaranfilskaKatri PylkäsGad RennertHedy S RennertKathryn J RuddyEmmanouil SaloustrosDale P SandlerElinor J SawyerRita K SchmutzlerChristopher ScottXiao-Ou ShuJacques SimardSnezhana SmichkoskaChristof SohnMelissa C SoutheyJohn J SpinelliJennifer StoneRulla M TamimiJack A TaylorRob A E M TollenaarIan P M TomlinsonMelissa A TroesterThérèse TruongCeline M VachonElke M van VeenSophia S WangClarice R WeinbergCamilla WendtHans WildiersRobert WinqvistAlicja WolkWei ZhengArgyrios ZiogasAlison M DunningPaul D P PharoahDouglas F EastonA Forbes HowieJulian PetoIsabel Dos-Santos-SilvaAnthony J SwerdlowJenny Chang-ClaudeMarjanka K SchmidtNick OrrOlivia FletcherPublished in: British journal of cancer (2021)
The CYP3A7*1C allele is associated with reduced risk of hormone receptor-positive breast cancer possibly mediated via an effect on the metabolism of endogenous sex hormones in premenopausal women.