Treatment of metastatic rectal squamous cell carcinoma in a pregnant patient.
Nathan S KauJeannie C KellyHyun KimRadhika SmithTyler J FraumKathleen ByrnesNikolaos A TrikalinosOlivia AranhaKevin Z LiShiyuan Anabeth LiuRama SureshPublished in: BMJ case reports (2024)
Rectal squamous cell carcinoma is an exceedingly rare form of rectal cancer, with limited data available regarding its presentation and effective treatment. Rectal cancer occurring during pregnancy is uncommon as well. This is a case of metastatic rectal squamous cell carcinoma presenting in a 22-week pregnant, female patient in her early 30s. The patient was treated with 5-fluorouracil and cisplatin and delivered a healthy male child born via uncomplicated vaginal delivery at 35 weeks. This article demonstrates that despite the rare nature of this cancer, in the already rare context of pregnancy, effective and safe treatment is possible with a multidisciplinary team.
Keyphrases
- squamous cell carcinoma
- rectal cancer
- locally advanced
- case report
- small cell lung cancer
- pregnant women
- lymph node metastasis
- combination therapy
- mental health
- machine learning
- clinical trial
- preterm birth
- young adults
- deep learning
- replacement therapy
- urinary tract infection
- gestational age
- study protocol
- data analysis
- double blind