Effects of Chronic Exposure to Mercury on Angiotensin-Converting Enzyme Activity and Oxidative Stress in Normotensive and Hypertensive Rats.

Dalton Valentim VassalloMaylla Ronacher SimõesKarina GiubertiBruna Fernandes AzevedoRogerio Faustino Ribeiro JuniorMercedes SalaicesIvanita Stefanon

Published in: Arquivos brasileiros de cardiologia (2019)

These results suggest that chronic exposure to inorganic mercury aggravates hypertension and produces more expressive changes in ACE activity and oxidative stress in SHRs. Such exposure affects the cardiovascular system, representing a risk factor for the development of cardiovascular disorders in normotensive rats and worsening of pre-existing risks for hypertension.

Keyphrases

angiotensin converting enzyme
oxidative stress
angiotensin ii
blood pressure
dna damage
ischemia reperfusion injury
diabetic rats
induced apoptosis
drug induced
climate change
water soluble
arterial hypertension