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Association of the genetic variants (-794 CATT5-8 and -173 G > C) of macrophage migration inhibitory factor (MIF) with higher soluble levels of MIF and TNFα in women with breast cancer.

Guadalupe Avalos-NavarroAlicia Del Toro-ArreolaAdrián Daneri-NavarroAntonio Quintero-RamosLuis Alberto Bautista-HerreraRamon Antonio Franco TopeteBrian Uriel Anaya MaciasDavid Israel Javalera CastroAndrés de Jesús Morán-MendozaAntonio Oceguera-VillanuevaAntonio Topete-CamachoJosé Francisco Munoz-Valle
Published in: Journal of clinical laboratory analysis (2020)
The functional variants of MIF are not genetic susceptibility markers for BC. Nevertheless, the alleles -173*C and -794CATT7 are associated with the increase of MIF circulating in women with BC.
Keyphrases
  • copy number
  • adipose tissue
  • genome wide
  • gene expression