Pien-Tze-Huang attenuates neuroinflammation in cerebral ischaemia-reperfusion injury in rats through the TLR4/NF-κB/MAPK pathway.
Xiaoqin ZhangQing ZhangLili HuangMingzhen LiuZaixing ChengYanfang ZhengWen XuJinjian LuJian LiuMing-Qing HuangPublished in: Pharmaceutical biology (2021)
PTH improved cerebral ischaemia-reperfusion injury by inhibiting neuroinflammation partly via the TLR4/NF-κB/MAPK signalling pathway, which will help guide its clinical application.
Keyphrases
- cerebral ischemia
- signaling pathway
- subarachnoid hemorrhage
- pi k akt
- toll like receptor
- inflammatory response
- brain injury
- blood brain barrier
- lps induced
- nuclear factor
- immune response
- oxidative stress
- lipopolysaccharide induced
- acute myocardial infarction
- heart failure
- cell proliferation
- acute coronary syndrome
- left ventricular