Clinical features and brain MRI volumetric changes in anti-mGluR5 encephalitis.
Yueqian SunJames X TaoXiong HanXiangqing WangYulan ZhuYajun LianGuoping RenWang QunPublished in: Annals of clinical and translational neurology (2023)
Our findings demonstrated that cognitive impairment, behavioral disturbance, seizures, and sleep disorder are the prominent clinical manifestations of anti-mGluR5 encephalitis. Most patients showed a good prognosis with full recovery, even in the paraneoplastic disease variants. The amygdala enlargement in the early and chronic disease stages is a distinct MRI feature, which exploratively offer a valuable perspective for the study of the disease processes.
Keyphrases
- cognitive impairment
- end stage renal disease
- magnetic resonance imaging
- contrast enhanced
- ejection fraction
- newly diagnosed
- chronic kidney disease
- resting state
- functional connectivity
- peritoneal dialysis
- physical activity
- diffusion weighted imaging
- machine learning
- computed tomography
- white matter
- magnetic resonance
- multiple sclerosis
- brain injury
- blood brain barrier
- temporal lobe epilepsy
- patient reported