Biocompatible Palladium Nanoparticles Prepared Using Vancomycin for Colorimetric Detection of Hydroquinone.
Shoubei GaoKai LiuXianbing JiYanshuai CuiRuyu LiGuanglong MaYongqiang ZhangLonggang WangPublished in: Polymers (2023)
Hydroquinone poses a major threat to human health and is refractory to degradation, so it is important to establish a convenient detection method. In this paper, we present a novel colorimetric method for the detection of hydroquinone based on a peroxidase-like Pd nanozyme. The vancomycin-stabilized palladium nanoparticles (Van-Pd n NPs, n = 0.5, 1, 2) were prepared using vancomycin as a biological template. The successful synthesis of Van-Pd n NPs (n = 0.5, 1, 2) was demonstrated by UV-vis spectrophotometry, transmission electron microscopy, and X-ray diffraction. The sizes of Pd nanoparticles inside Van-Pd 0.5 NPs, Van-Pd 1 NPs, and Van-Pd 2 NPs were 2.6 ± 0.5 nm, 2.9 ± 0.6 nm, and 4.3 ± 0.5 nm, respectively. Furthermore, Van-Pd 2 NPs exhibited excellent biocompatibility based on the MTT assay. More importantly, Van-Pd 2 NPs had good peroxidase-like activity. A reliable hydroquinone detection method was established based on the peroxidase-like activity of Van-Pd 2 NPs, and the detection limit was as low as 0.323 μM. Therefore, vancomycin improved the peroxidase-like activity and biocompatibility of Van-Pd 2 NPs. Van-Pd 2 NPs have good application prospects in the colorimetric detection of hydroquinone.
Keyphrases
- hydrogen peroxide
- gold nanoparticles
- label free
- loop mediated isothermal amplification
- oxide nanoparticles
- human health
- magnetic resonance imaging
- methicillin resistant staphylococcus aureus
- sensitive detection
- nitric oxide
- computed tomography
- climate change
- staphylococcus aureus
- living cells
- fluorescent probe
- single cell
- quantum dots
- simultaneous determination
- dual energy