N-acetyltransferase 10 facilitates tumorigenesis of diffuse large B-cell lymphoma by regulating AMPK/mTOR signalling through N4-acetylcytidine modification of SLC30A9.

Mengfei DingZhuoya YuTiange LuShunfeng HuXiangxiang ZhouXin Wang

Published in: Clinical and translational medicine (2024)

Collectively, these findings highlighted the essential role of ac4C RNA modification mediated by NAT10 in DLBCL, and provided insights into novel epigenetic-based therapeutic strategies.

Keyphrases

diffuse large b cell lymphoma
epstein barr virus
dna methylation
gene expression
cell proliferation
skeletal muscle
protein kinase