The development of a rapid patient-derive d xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors.

Martine CharbonneauKelly HarperKarine Brochu-GaudreauAlexis PerreaultLaurent-Olivier RoyFabrice LucienShulan TianDavid FortinClaire M Dubois

Published in: Neuro-oncology (2023)

The CAM-glioma model is a fast and reliable assay that has the potential to serve as a complementary model to drug discovery and a real-time Avatar platform to predict the best treatment for HGG patients.

Keyphrases

drug discovery
high throughput
end stage renal disease
case report
prognostic factors
risk assessment
spinal cord
neuropathic pain
single cell
adverse drug
electronic health record
drug induced