Genetic testing in Poland and Ukraine: should comprehensive germline testing of BRCA1 and BRCA2 be recommended for women with breast and ovarian cancer?

Tu Nguyen-DumontPawel KarpinskiMaria M SasiadekHayane AkopyanJason A SteenDerrick TheysFleur HammetHelen TsimiklisDaniel J Park Bernard J PopeRyszard SlezakAgnieszka StembalskaKarolina PeszNataliya KitseraAleksandra SiekierzynskaMelissa C SoutheyAleksander Myszka

Published in: Genetics research (2020)

These results indicate that genetic testing in women at high risk of breast and ovarian cancer in Poland and Ukraine should not be limited to founder mutations. Extended testing will enhance risk stratification and management for these women and their families.

Keyphrases

breast cancer risk
polycystic ovary syndrome
pregnancy outcomes
cervical cancer screening
dna repair
pregnant women
oxidative stress
metabolic syndrome
adipose tissue