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From Bench to Bedside in Rheumatoid Arthritis from the "2022 GISEA International Symposium".

Antonio VitaleStefano AliverniniRoberto CaporaliGiulia CassoneDario BrunoClaudia FabianiGiuseppe LopalcoMaurizio RossiniFabiola AtzeniEnnio Giulio FavalliFabrizio ContiElisa GremeseFlorenzo IannoneGian Franco FerraccioliGiovanni LapadulaMarco Sebastiani
Published in: Journal of clinical medicine (2023)
While precision medicine is still a challenge in rheumatic disease, in recent years many advances have been made regarding pathogenesis, the treatment of inflammatory arthropathies, and their interaction. New insight into the role of inflammasome and synovial tissue macrophage subsets as predictors of drug response give hope for future tailored therapeutic strategies and a personalized medicine approach in inflammatory arthropathies. Here, we discuss the main pathogenetic mechanisms and therapeutic approaches towards precision medicine in rheumatoid arthritis from the 2022 International GISEA/OEG Symposium.
Keyphrases
  • rheumatoid arthritis
  • disease activity
  • oxidative stress
  • interstitial lung disease
  • ankylosing spondylitis
  • adipose tissue
  • current status
  • peripheral blood
  • combination therapy
  • adverse drug
  • drug induced