Disturbed atrial metabolism, shear stress, and cardiac load AF after ablation: AXAFA biomolecule study.
Winnie ChuaAlya KhashabaHansel CanagarajahJens Cosedis NielsenLuigi Di BiaseKarl Georg HaeuslerGerhard HindricksLluis MontJonathan P PicciniRenate B SchnabelUlrich SchottenUrsula-Henrike Wienhues-ThelenTanja ZellerLarissa FabritzPaulus F KirchhofPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)
Elevated concentrations of ANGPT2, BMP10 and NT-proBNP are associated with recurrent atrial fibrillation after a first AF ablation, suggesting that processes linked to disturbed cardiomyocyte metabolism, altered atrial shear stress, and increased load contribute to atrial fibrillation after AF ablation in patients.
Keyphrases
- atrial fibrillation
- catheter ablation
- left atrial
- left atrial appendage
- oral anticoagulants
- direct oral anticoagulants
- heart failure
- end stage renal disease
- percutaneous coronary intervention
- ejection fraction
- newly diagnosed
- radiofrequency ablation
- chronic kidney disease
- left ventricular
- mesenchymal stem cells
- bone marrow
- venous thromboembolism
- patient reported
- mitral valve
- high glucose