Role of the mononuclear cell infiltrate in Graves' orbitopathy (GO): results of a large cohort study.
G Rotondo DottoreL TorregrossaG LanzollaS MariottiF MenconiP PiaggiL Cristofani MencacciC PosarelliM N MaglionicoI DallanM FigusM NardiC MarcocciF BasoloMichele MarinòPublished in: Journal of endocrinological investigation (2021)
Mononuclear cell infiltrates are present in the majority of GO patients, with a small percentage represented exclusively by plasmacells. CD4 cells exert a major role on GO activity. These findings may represent a further advancement in the comprehension of GO pathogenesis.