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The choice of embedding media affects image quality, tissue R2 * , and susceptibility behaviors in post-mortem brain MR microscopy at 7.0T.

Petr DušekVince Istvan MadaiTill HuelnhagenErik BahnRadoslav MatejJan SobeskyThoralf NiendorfJulio Acosta-CabroneroJens Wuerfel
Published in: Magnetic resonance in medicine (2018)
Embedding media affect gradient-echo image quality, R2 * , and QSM in differing ways. In this study, PBS embedding was identified as the most stable experimental setup, although by a small margin. Agarose and Galden were preferred to formalin or D2 O embedding. Formalin significantly increased R2 * causing noisier data and increased QSM variance.
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