Unraveling the Interaction of Aspirin, Ticagrelor, and Rosuvastatin on the Progression of Atherosclerosis and Inflammation in Diabetic Mice.
Yumei YeSven NylanderYochai BirnbaumPublished in: Cardiovascular drugs and therapy (2018)
We found an intricate interaction between aspirin, ticagrelor, and rosuvastatin, as aspirin reduced both ticagrelor and rosuvastatin ability to ameliorate inflammation and atherosclerosis. In contrast, we found additive effects when ticagrelor and rosuvastatin were combined.
Keyphrases
- antiplatelet therapy
- acute coronary syndrome
- percutaneous coronary intervention
- st segment elevation myocardial infarction
- low dose
- st elevation myocardial infarction
- oxidative stress
- cardiovascular events
- cardiovascular disease
- coronary artery disease
- magnetic resonance
- type diabetes
- magnetic resonance imaging
- anti inflammatory drugs
- computed tomography