Management of early stage HER2 positive breast cancer and increased implementation of axillary imaging to improve identification of nodal metastasis.

Rachel L McCaffreyJessica L ThompsonRebecca H OudsemaAndrew P SciallisErin F CobainMichael S SabelJacqueline S Jeruss

Published in: Journal of surgical oncology (2022)

We identified a 24% nodal positivity rate in clinically node negative T1 HER2+ breast cancer patients. In particular, HER2+ patients with high-grade T1c cancers should undergo preoperative diagnostic axillary imaging to expand potential benefit from targeted therapies.

Keyphrases

lymph node
neoadjuvant chemotherapy
positive breast cancer
early stage
sentinel lymph node
high grade
high resolution
healthcare
primary care
low grade
ultrasound guided
radiation therapy
risk assessment
human health
mass spectrometry
climate change