Neutrophil extracellular trap formation and its implications in nonsteroidal anti-inflammatory drug-induced small intestinal injury.

Eiji MoriyamaYuji NadataniAkira HigashimoriKoji OtaniMasaki OminamiShusei FukunagaShuhei HosomiFumio TanakaKoichi TairaYasuhiro FujiwaraToshio Watanabe

Published in: Journal of gastroenterology and hepatology (2024)

These results suggest that NETs aggravate NSAID-induced small intestinal injury. Therefore, NET inhibition could be a potential treatment for NSAID-induced small intestinal injury.

Keyphrases

drug induced
liver injury
high glucose
diabetic rats
anti inflammatory
oxidative stress
endothelial cells
risk assessment
combination therapy
human health