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No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa.

Tomas WeinertFabio BernardoniJoseph KingJulius StedingIlka BoehmMerle MannigelFranziska RitschelFlorian ZepfVeit RoessnerStefan Ehrlich
Published in: European archives of psychiatry and clinical neuroscience (2022)
Our results do not support the hypothesis that short-term depletion of TRP and its impact on the brain 5-HT reduces anxiety or improves mood in AN. As the evidence for the role of 5-HT dysfunction on affective processes in patients with AN is limited, further studies are needed to assess its relevance in the pathophysiology of AN.
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