No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa.
Tomas WeinertFabio BernardoniJoseph KingJulius StedingIlka BoehmMerle MannigelFranziska RitschelFlorian ZepfVeit RoessnerStefan EhrlichPublished in: European archives of psychiatry and clinical neuroscience (2022)
Our results do not support the hypothesis that short-term depletion of TRP and its impact on the brain 5-HT reduces anxiety or improves mood in AN. As the evidence for the role of 5-HT dysfunction on affective processes in patients with AN is limited, further studies are needed to assess its relevance in the pathophysiology of AN.
Keyphrases
- sleep quality
- anorexia nervosa
- bipolar disorder
- physical activity
- liver failure
- depressive symptoms
- body mass index
- oxidative stress
- resting state
- white matter
- weight loss
- respiratory failure
- case control
- drug induced
- weight gain
- aortic dissection
- functional connectivity
- multiple sclerosis
- hepatitis b virus
- intensive care unit
- cerebral ischemia
- mechanical ventilation