Biopsy prostate cancer perineural invasion and tumour load are associated with positive posterolateral margins at radical prostatectomy: implications for planning of nerve-sparing surgery.
Margaretha A van der SlotSebastiaan RemmersCharlotte F KweldamMichael A den BakkerDaan NieboerMartijn B BusstraMelanie GanSjoerd KlaverJohn B W RietbergenG J L H Geert van Leendersnull nullPublished in: Histopathology (2023)
Ipsilateral PNI and percentage of positive cores were significant predictors for a positive posterolateral surgical margin at RP. Biopsy PNI and tumour volume can therefore support clinical decision-making on the level of nerve-sparing surgery in prostate cancer patients.