Login / Signup

All-in-One Synthesis of 3,6-Dideoxysugars: An Olefin Metathesis-Isomerization Approach.

Hongwei ChenZuming LinYuan MengJian LiSha-Hua HuangRan Hong
Published in: Organic letters (2023)
A collective synthesis of 3,6-dideoxysugars, including seven naturally known congeners, has been reported using commercially available methyl lactates in five steps. The essential tandem process involving the olefin cross-metathesis and isomerization steps was enabled by the dual function of Grubbs-II catalyst, affording the products in good yields and providing concise and practical access to a class of biologically important deoxysugars.
Keyphrases
  • highly efficient
  • reduced graphene oxide
  • metal organic framework