Target Capture/Next-Generation Sequencing for Nonsyndromic Cleft Lip and Palate in the Japanese Population.
Masayasu ShibanoAkira WatanabeNobuo TakanoHiroyuki MishimaAkira KinoshitaKoh-Ichiro YoshiuraTakahiko ShibaharaPublished in: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association (2019)
The DLX4 missense mutation c.359C>T (Pro120Leu) was found in 1 Japanese patient with NSCL±P and was located in the homeodomain region. This mutation likely plays a role in the development of NSCL±P in the Japanese population.