Relationship between hemoglobin, hemolysis, and transcranial Doppler velocities in children with sickle cell disease: Results from a long-term natural history study in Italy in the era of multimodal therapy.

Giulia ReggianiBeatrice CoppadoroVania MunarettoAlessio PieroniFederica ViaroRenzo ManaraAnne BeaubrunAlessandra BiffiClaudio BaracchiniLaura SainatiRaffaella Colombatti

Published in: European journal of haematology (2023)

These results support the need to optimize disease-modifying treatments that increase Hb and reduce hemolysis for stroke prevention in young children with SCD.

Keyphrases

red blood cell
young adults
stem cells
brain injury
bone marrow
blood brain barrier
chronic pain