Cavβ3 Contributes to the Maintenance of the Blood-Brain Barrier and Alleviates Symptoms of Experimental Autoimmune Encephalomyelitis.

Damian MartusSarah K WilliamsKira PichiStefanie Mannebach-GötzNicolas KaiserBarbara WardasClaudia Fecher-TrostMarkus R Meyer Frank SchmitzAndreas BeckRichard Fairless Ricarda Diem Veit Flockerzi Anouar Belkacemi

Published in: Arteriosclerosis, thrombosis, and vascular biology (2024)

-dependent MLC phosphorylation in BMECs, and this role of Cavβ3 in BMECs contributes to blood-brain barrier integrity and attenuates the severity of experimental autoimmune encephalomyelitis disease.

Keyphrases

blood brain barrier
cerebral ischemia
mouse model
protein kinase
physical activity
depressive symptoms