Early-stage multi-differentiated gastric carcinosarcoma and post-resection local recurrence: a case report.
Akihiro ShioyaNozomu KuroseKenichi MizutaniMotona KumagaiKen KawauraNaohiko NakamuraTakeo KosakaNozomu MotonoHidetaka UramotoSohsuke YamadaPublished in: Diagnostic pathology (2020)
Few cases of early-stage gastric carcinosarcoma have been reported, but there are no reports of recurrence to date. Local recurrence as in this patient, and even in early-stage cases, requires cautious surveillance to check for post-resection recurrence and metastasis. The etiopathogenesis of carcinosarcoma has not yet been elucidated; however, in the present case, despite the tumor's relatively small size, it exhibited various types of differentiation in both the carcinomatous and sarcomatous components and a proliferative germ cell-like portion, which suggests that the monoclonal origin hypothesis may be a valid theory for the carcinosarcoma.