The Role of Trace Elements in Pseudoexfoliation Syndrome: A Cross-sectional Study.
Mohammad Reza TalebnejadAli AzimiMohammad Reza KhaliliAidin MeshksarPublished in: Journal of ophthalmic & vision research (2021)
Our study demonstrated that the serum iron and zinc levels were lower in PXF patients. Nutritional deficiency may be a cause of zonular weakness in these patients. Heme is a cofactor for the enzyme which contributes to the biosynthesis of fibrillin, the major protein in zonular fibers. Therefore, iron can play a substantial role in the biosynthesis of the fibrils and also in the zonular stability.