Login / Signup

PI3KCA Mutations in Uterine Cervix Carcinoma.

Ioannis A Voutsadakis
Published in: Journal of clinical medicine (2021)
Frequent mutations of PIK3CA gene in squamous cervical carcinomas may represent an opportunity for targeted therapies development both inhibiting the PI3K kinase and associated pathway defects. Increased TMB may additionally confer immunotherapy sensitivity.
Keyphrases
  • high grade
  • protein kinase
  • signaling pathway
  • low grade
  • genome wide
  • copy number
  • dna methylation
  • genome wide identification