Clinical Validation of an Immune Quiescence Gene Expression Signature in Kidney Transplantation.
Enver AkalinMatthew R WeirSuphamai BunnapradistDaniel C BrennanRowena Delos SantosAnthony LangoneArjang DjamaliHua XuXia JinShamik DholakiaRobert N WoodwardJonathan S BrombergPublished in: Kidney360 (2021)
Validation of AlloMap Kidney demonstrated the ability to differentiate between rejection and immune quiescence using a range of scores. The diagnostic performance suggests that assessment of the mechanisms of immunologic activity is complementary to allograft injury information derived from AlloSure dd-cfDNA. Together, these biomarkers offer a more comprehensive assessment of allograft health and immune quiescence.