Redefining Perineural Invasion in Head and Neck Cutaneous Squamous Cell Carcinoma.
Erin R CohenCarly I MisztalCortney DableCarmen Gomez-FernandezRita G BhatiaPatrick RothRuixuan MaSamuel TrosmanCarlos GreenElizabeth NicolliChristine T DinhZoukaa B SargiPublished in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (2022)
DFS was significantly worse in patients with PNI, facial nerve weakness, advanced T stage, positive margins, and multiple nerve involvement. Further characterization of PNI features may help improve prognostic predictions and identify patients who may benefit from more aggressive treatment.