Successful Treatment of Respiratory Failure in a Patient with Prader-Willi Syndrome with Noninvasive Ventilation with AVAPS.
Nauras HwigMontserrat Diaz-AbadVictor T PengJennifer Y SoAnayansi Lasso-PirotPublished in: Case reports in medicine (2023)
Prader-Willi syndrome (PWS) is the most prevalent syndromic form of obesity, which starts during early childhood in the setting of hyperphagia. Due to the development of obesity, there is a high prevalence of obstructive sleep apnea (OSA) among these patients. This case report presents a patient with PWS with morbid obesity, severe OSA, and obesity hypoventilation syndrome admitted to the hospital for hypoxemic and hypercapnic respiratory failure. Noninvasive ventilation (NIV) with average volume-assured pressure support, a newer NIV modality, was used successfully to treat this patient, achieving major clinical and gas exchange improvement both during the hospitalization and long term after discharge.
Keyphrases
- respiratory failure
- case report
- obstructive sleep apnea
- extracorporeal membrane oxygenation
- insulin resistance
- metabolic syndrome
- mechanical ventilation
- weight loss
- high fat diet induced
- type diabetes
- positive airway pressure
- weight gain
- bariatric surgery
- growth hormone
- acute respiratory distress syndrome
- end stage renal disease
- newly diagnosed
- intensive care unit
- emergency department
- chronic kidney disease
- healthcare
- early onset
- sleep apnea
- room temperature
- patient reported
- autism spectrum disorder
- obese patients
- patient reported outcomes
- drug induced