Reprogramming of 3D genome structure underlying HSPC development in zebrafish.

Min HeXiaoli LiBingxiang XuYinbo LuJingyi LaiYiming LingHuakai LiuZiyang AnWenqing ZhangFeifei Li

Published in: Stem cell research & therapy (2024)

Our results provided a global view of chromatin structure dynamics associated with development of zebrafish HSPC and discovered key transcription factors involved in HSPC chromatin interactions, which will provide new insights into the epigenetic regulatory mechanisms underlying vertebrate HSPC fate decision.

Keyphrases

transcription factor
gene expression
genome wide
dna damage
dna methylation
dna binding
oxidative stress
decision making