The Role and Mechanism of Hyperoside against Depression-like Behavior in Mice via the NLRP1 Inflammasome.

Aoqi SongZhenghua WuWenjuan ZhaoWenqing ShiRu ChengJingjing JiangZhuojun NiHan QuXijier QiaolongbatuGuorong FanYuefen Lou

Published in: Medicina (Kaunas, Lithuania) (2022)

Hyp is one of the main active components of HP, and Hyp has antidepressant effects through the NLRP1 inflammasome, which may be connected with the CXCL1/CXCR2/BDNF signaling pathway.

Keyphrases

nlrp inflammasome
signaling pathway
major depressive disorder
depressive symptoms
high fat diet induced
epithelial mesenchymal transition
sleep quality
induced apoptosis
cell migration
oxidative stress
cell proliferation
wild type
skeletal muscle
endoplasmic reticulum stress