Relationship of Streptococcus mutans with valvar cardiac tissue: A molecular and immunohistochemical study.
Francisco Artur Forte OliveiraClarissa Pessoa Fernandes FortePaulo Goberlânio de Barros SilvaCamile de Barros LopesRaquel Carvalho MontenegroÂndrea Kely Campos Ribeiro Dos SantosMário Rogério Lima MotaFabrício Bitu SousaAna Paula Negreiros Nunes AlvesPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2019)
Streptococcus mutans was found in the oral cavity, healthy valve tissue, and calcified aortic stenosis samples. However, the microorganism was visualized by immunohistochemistry only in the calcified aortic stenosis samples, which may suggest viability and an increased bacterial density in this condition. The association of the presence of S mutans and positive CD61 immunoexpression suggests a probable relationship with calcified aortic stenosis.
Keyphrases
- aortic stenosis
- biofilm formation
- candida albicans
- left ventricular
- transcatheter aortic valve replacement
- ejection fraction
- aortic valve
- aortic valve replacement
- transcatheter aortic valve implantation
- pseudomonas aeruginosa
- staphylococcus aureus
- escherichia coli
- coronary artery disease
- mitral valve
- cystic fibrosis
- atrial fibrillation