Functional Outcome and Hemorrhage Rates After Bridging Therapy With Tenecteplase or Alteplase in Patients With Large Ischemic Core.
Gaspard GerschenfeldGuillaume TurcMichael ObadiaNicolas ChaussonArturo ConsoliStephane OlindoJildaz CaroffGaultier MarnatRaphaël BlancWagih Ben HassenPierre SenersBenoît GuillonEmmanuel WienerRomain BourcierMarion YgerTae-Hee ChoThomas CheckouriBenjamin GoryDidier SmadjaIgor Paul SibonSébastien RichardBasile OndzeOmer Faruk EkerFernando PicoBertrand LapergueSonia Alamowitchnull nullPublished in: Neurology (2024)
This study provides Class III evidence that patients with anterior circulation LVO stroke and DWI-ASPECTS ≤5 treated with tenecteplase vs alteplase before MT experienced better functional outcomes and lower mortality at 3 months.
Keyphrases
- acute ischemic stroke
- atrial fibrillation
- cardiovascular events
- cerebral ischemia
- risk factors
- stem cells
- cardiovascular disease
- type diabetes
- ischemia reperfusion injury
- computed tomography
- magnetic resonance imaging
- magnetic resonance
- coronary artery disease
- oxidative stress
- mesenchymal stem cells
- brain injury
- subarachnoid hemorrhage
- newly diagnosed
- cell therapy