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BRAF and KRAS mutations in papillary thyroid carcinoma in the United Arab Emirates.

Suhail Al-SalamCharu SharmaBachar O AfandiKhaled Al DahmaniAli S Al-ZahraniAmal Al ShamsiJuma Al Kaabi
Published in: PloS one (2020)
BRAF V600E and KRAS mutation are seen in a significant number of PTC in the UAE. BRAF mutation is significantly correlated with large tumor size, positive surgical margins and lymph node metastasis suggesting an association between BRAF V600E mutation and tumor growth and spread.
Keyphrases
  • wild type
  • lymph node metastasis
  • metastatic colorectal cancer
  • squamous cell carcinoma
  • papillary thyroid
  • lymph node