TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma.

Wei ZhangJin LiYaping WuHan GeYue SongDongmiao WangHua YuanHongbing JiangYanling WangJie Cheng

Published in: Cancer cell international (2018)

Our findings reveal that TEAD4 serves as a novel prognostic biomarker and putative oncogene for HNSCC by promoting cell proliferation, migration and invasion, and EMT.

Keyphrases

epithelial mesenchymal transition
cell proliferation
squamous cell carcinoma
transforming growth factor
signaling pathway
cell cycle
genome wide
optic nerve
pi k akt
single cell
locally advanced
lymph node metastasis
transcription factor
gene expression
dna methylation
radiation therapy
electronic health record