Melanin-concentrating hormone regulates the hypercapnic chemoreflex by acting in the lateral hypothalamic area.
Laísa T C RodriguesLuis Gustavo A PatroneLuciane Helena GargaglioniMirela B DiasPublished in: Experimental physiology (2022)
ventilatory response during wakefulness and sleep in the light period, while SNAP-94847 intra-LHA increased this response, during wakefulness in the light period. In the LC, MCH or the MCH1-R antagonist caused no change in the hypercapnic ventilatory response. Our results suggest that MCH, in the LHA, exerts an inhibitory modulation of the hypercapnic ventilatory response during the light-inactive period in rats.