Login / Signup

Kinetics of torquetenovirus DNA load in a recent kidney transplant recipient with mild SARS-CoV-2 infection and a failed antibody response.

Sara QueridoAna Rita CalçaAndré WeigertDiogo FranciscoTeresa AdragãoMaria Ana PessanhaPerpétua GomesLuís RodriguesJoão M FigueiraConceição CardosoDomingos Machado
Published in: Transplant infectious disease : an official journal of the Transplantation Society (2020)
Kidney transplant (KT) recipients are at an increased risk for severe COVID-19 because of their immunosuppressed state. A 42-year-old KT patient was diagnosed with COVID-19 three months after KT. Despite lymphopenia and several risk factors, he had a mild disease course. Nasopharyngeal real-time reverse transcriptase polymerase chain reaction for SARS-CoV-2 became negative 48 days after detection. SARS-CoV-2 IgG antibodies became negative after day 40. TTV DNA load increased with the onset COVID-19 and reduced after its resolution. This is the first report where TTV DNA load was measured during the course of COVID-19.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • coronavirus disease
  • single molecule
  • circulating tumor
  • risk factors
  • cell free
  • case report
  • nucleic acid
  • kidney transplantation
  • circulating tumor cells
  • drug induced