Proteomics profiling reveals a distinct high-risk molecular subtype of hypertrophic cardiomyopathy.

Lusha W LiangYoshihiko RaitaKohei HasegawaMichael A FiferMathew S MaurerMuredach P ReillyYuichi J Shimada

Published in: Heart (British Cardiac Society) (2022)

Our prospective plasma proteomics study not only exhibited the presence of HCM molecular subtypes but also identified pathobiological mechanisms associated with a distinct high-risk subtype of HCM.

Keyphrases

hypertrophic cardiomyopathy
left ventricular
mass spectrometry
label free
single molecule
single cell
heart failure