Improved diagnosis of reflux hypersensitivity.
Theodoros A VoulgarisShintaro HoshinoDaniel SifrimEtsuro YazakiPublished in: Neurogastroenterology and motility (2023)
Some PPI responsiveness is frequent among patients with RH as also with FH, and cannot discriminate those entities clinically when diagnosing RH using SI and/or SAP positive criterion. Patients with RH and SI/SAP concordance differ from patients without. Implementation of a strict RH definition (both SI and SAP positive) can better distinguish RH from FH and should be used in the future.