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Obesity in adult acute myeloid leukemia is not associated with inferior response or survival even when dose capping anthracyclines: An ECOG-ACRIN analysis.

James M ForanZhuoxin SunCatherine E LaiHugo F FernandezLarry D CripeRhett P KetterlingJanis RacevskisSelina M LugerElisabeth PaiettaHillard M LazarusYanming ZhangJohn M BennettRoss L LevineJacob M RoweMark R LitzowMartin S Tallman
Published in: Cancer (2023)
Obesity is associated with unique clinical and disease-related phenotypic features in AML and may influence physician treatment decisions regarding daunorubicin dosing. However, the current study demonstrates that obesity is not a factor in survival, and strict adherence to body surface area-based dosing is not necessary because dose adjustments do not affect outcomes.
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