LETM1 Promotes Gastric Cancer Cell Proliferation, Migration, and Invasion via the PI3K/Akt Signaling Pathway.

Yunfeng Zhang Lele Chen Yifan Cao Si Chen Chao Xu Jun Xing Kaiguang Zhang

Published in: Journal of gastric cancer (2020)

LETM1 acts as an oncogenic gene to promote GC cell proliferation, migration, and invasion via the PI3K/Akt signaling pathway. Therefore, LETM1 may be a potential target for GC diagnosis and treatment.

Keyphrases

cell proliferation
pi k akt
signaling pathway
cell cycle
epithelial mesenchymal transition
induced apoptosis
gas chromatography
genome wide
transcription factor
risk assessment
high resolution
tandem mass spectrometry
genome wide analysis