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Melatonin Inhibits Chemical Carcinogen-mediated Malignant Transformation of Urothelial Cells: In Vitro Evidence.
Yujiro Nagata
Nguyen Thu Quynh
Hisami Aono
Kenichi Harada
Hiroshi Miyamoto
Naohiro Fujimoto
Published in:
Cancer genomics & proteomics (2024)
These findings indicate that melatonin serves as a suppressor for urothelial tumorigenesis. To the best of our knowledge, this is the first preclinical study demonstrating the impact of melatonin on the development of urothelial cancer.
Keyphrases
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urinary tract
high grade
induced apoptosis
papillary thyroid
healthcare
stem cells
squamous cell carcinoma
cell therapy
endoplasmic reticulum stress
signaling pathway
lymph node metastasis