Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma.
Sven H LoosenGeorg LurjeGeorg WiltbergerMihael VucurAlexander KochJakob N KatherPia PaffenholzFrank TackeFlorian T UlmerChristian TrautweinTom LueddeUlf P NeumannChristoph RoderburgPublished in: PloS one (2019)
Analysis of circulating miRNAs represents a promising tool for the diagnosis of even early stage CCA. A postoperative decline in miRNA serum concentrations might be indicative for a favorable patients' outcome and helpful to identify patients with a good prognosis after extended liver surgery.
Keyphrases
- cell proliferation
- long non coding rna
- long noncoding rna
- early stage
- end stage renal disease
- minimally invasive
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- squamous cell carcinoma
- radiation therapy
- acute coronary syndrome
- lymph node
- patient reported outcomes
- coronary artery bypass
- locally advanced