Fimasartan Ameliorates Deteriorations in Glucose Metabolism in a High Glucose State by Regulating Skeletal Muscle and Liver Cells.

You-Na Jang Yong-Jik Lee Yoon Mi Han Hyun Min Kim Hong Seog Seo Ji Hoon Jeong Seung Yeon Park Tae Woo Jung

Published in: Yonsei medical journal (2022)

In conclusion, fimasartan ameliorates deteriorations in glucose metabolism as a result of a high glucose state by regulating PPARδ in skeletal muscle and liver cells.

Keyphrases

high glucose
skeletal muscle
endothelial cells
induced apoptosis
insulin resistance
cell cycle arrest
endoplasmic reticulum stress
mouse model
oxidative stress
type diabetes
signaling pathway
metabolic syndrome
adipose tissue