Pulmonary Hypertension Induced by Right Pulmonary Artery Occlusion: Hemodynamic Consequences of Bmpr2 Mutation.
Alban TodescoJulien GrynblatKouamé Kan Firmin AkoumiaDamien BonnetPedro Mendes-FerreiraStephane MorissetDenis ChemlaMarilyne LevyMathilde MeotSophie-Guiti Malekzadeh-MilaniBirger TielemansBenoit DecanteCarine Vastel-AmzallagPaul HabertMaria-Rosa GhignaMarc HumbertI David MontaniDavid BoulateFrédéric PerrosPublished in: Journal of the American Heart Association (2024)
Our novel 2-hit rat model presents a promising avenue to explore the adaptation of the right ventricle and pulmonary vasculature to PH, shedding light on pertinent sex- and gene-related effects.