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Late-onset and congenital hearing loss detected using AABR due to congenital cytomegalovirus infection that improved with valganciclovir.

Chihiro MorimotoToshiya NishikuboTadashi NishimuraTomoko OnishiMasahiro TakeyamaYumiko UchidaShintaro OtsukaToshiaki YamanakaTadashi Kitahara
Published in: Congenital anomalies (2022)
Congenital cytomegalovirus (cCMV) infection is the most common congenital viral infection and is the leading non-genetic cause of sensorineural hearing loss and an important cause of neurodevelopmental disabilities. Auto auditory brainstem response (AABR) is a simple hearing test and used for the purpose of neonatal hearing screening, but can use it for early detection hard of hearing within the study age of the model. We experienced two case of asymptomatic CMV infection in which congenital and late-onset hearing loss were diagnosed early with AABR, and hearing loss improved with valganciclovir.
Keyphrases
  • hearing loss
  • late onset
  • early onset
  • dna methylation
  • copy number