The mediating role of bariatric surgery in the metabolic relationship between parathyroid hormone and 25-hydroxyvitamin D.
Maryam BarzinAmir EbadinejadFarnaz VahidiAlireza KhalajMaryam MahdaviMajid ValizadehFarhad HosseinpanahPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2022)
In patients with severe obesity, PTH was suppressed at a relatively lower concentration of 25(OH)D; this threshold increased following surgery-induced weight loss. These findings suggest a role for bariatric surgery in regulating 25(OH)D metabolism in patients with obesity.
Keyphrases
- weight loss
- bariatric surgery
- obese patients
- roux en y gastric bypass
- gastric bypass
- minimally invasive
- weight gain
- coronary artery bypass
- drug induced
- glycemic control
- diabetic rats
- high glucose
- insulin resistance
- metabolic syndrome
- type diabetes
- early onset
- oxidative stress
- adipose tissue
- coronary artery disease
- skeletal muscle
- physical activity