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Gold Nanoparticles Enhance the Tumor Growth-Suppressing Effects of Cetuximab and Radiotherapy in Head and Neck Cancer In Vitro and In Vivo.

Takumi SatoYasumasa KakeiTakumi HasegawaMasahiko KashinShun TeraokaAkinobu YamaguchiRyohei SasakiMasaya Akashi
Published in: Cancers (2023)
This study showed that AuNPs alone do not have a tumor-suppressing effect, but they sensitize tumors to radiotherapy and bind to cetuximab, leading to enhanced antitumor effects.
Keyphrases
  • locally advanced
  • gold nanoparticles
  • early stage
  • rectal cancer
  • radiation therapy
  • signaling pathway
  • squamous cell carcinoma
  • radiation induced
  • metastatic colorectal cancer
  • wild type
  • reduced graphene oxide