Immunosuppression reduction in liver and kidney transplant recipients with suspected bacterial infection: A multinational survey.
Daniel ShepshelovichNoam TauHefziba GreenBenaya Rozen-ZviAssaf IssascharMarco FalconeJulien CoussementOren ZusmanOriol ManuelEytan MorJulian Torre-CisnerosDafna YahavPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2019)
Immunosuppression management during bacterial infection is heterogenous in US and European centers. Immunosupression reduction (ISR) during infection is a common practice, though supported by limited evidence. Demonstrating high heterogeneity in the approach to ISR, together with the equivocal results of clinical studies, support consideration of an interventional clinical trial.